| CatalogCode: | H00002645-M01 |
| ProductName: | GCK Antibody |
| Product Description: | Mouse Monoclonal anti-GCK (3C7) |
| Clone: | 3C7 |
| Clonality: | Monoclonal |
| Immunogen: | GCK (AAH01890, 356 a.a. ~ 465 a.a) partial recombinant protein with GST tag. |
| Epitope: | GLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ ... |
| Specificity: | GCK - glucokinase (hexokinase 4, maturity onset diabetes of the young 2) |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg IgG purified Mouse ascites. |
| Uses: | Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. |
| Background: | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG1 Kappa |
| Host_Name: | Mouse |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-GK antibody, anti-GLK antibody, anti-HK4 antibody, anti-HKIV antibody, anti-HXKP antibody, anti-MODY2 antibody |
| ProteinTarget: | GCK - glucokinase (hexokinase 4, maturity onset diabetes of the young 2) |
| PackageSize: | 0.1 mg |
| NotesMain: | This antibody is available only in North America and is supplied by Abnova If in stock in Taiwan. delivery is 10-14 days. If not in stock. lead times can be extended. We will inform you of any extended delays within 48 hours. The immunizing protein is also available for this product. Unit cost for the protein is $ 250 (2 ug). $ 305 (10 ug). and $ 445 (25 ug). |
| Gene_Id: | 2645 |
| Gene_Symbol: | GCK |
| Omim_ID: | 125851, 138079, 602485, 606176, |
order or
more information: | company product webpage |
| request information: |
|