| CatalogCode: | | H00000867-A01 |
| ProductName: | | CBL Antibody |
| Product Description: | | Mouse Polyclonal anti-CBL |
| Clonality: | | Polyclonal |
| Immunogen: | | CBL (NP_005179, 736 a.a. ~ 835 a.a) partial recombinant protein with GST tag. |
| Epitope: | | NIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSER* ... |
| Specificity: | | CBL - Cas-Br-M (murine) ecotropic retroviral transforming sequence |
| CrossReactivity: | | Human. Other species not tested. |
| Packaging: | | 0.05 ml of mouse antisera with 50% glycerol. No preservative. |
| Uses: | | The quality control of this antibody is limited to Western blot on the immunizing protein.
Abnova's recommended working dilutions for western analysis are as follows:
1:500 dilution for ascites
1:1000 for purified Ig
1:500-1:1000 for polysera |
| Background: | | The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. |
| Storage: | | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | | Whole antisera |
| Host_Name: | | Mouse |
| ListPrice: | | 225 |
| AppSummary: | | ELISA, WB |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-C-CBL antibody, anti-CBL2 antibody, anti-RNF55 antibody |
| ProteinTarget: | | CBL - Cas-Br-M (murine) ecotropic retroviral transforming sequence |
| PackageSize: | | 0.05 ml |
| NotesMain: | | This antibody is available only in North America and is supplied by Abnova If in stock in Taiwan. delivery is 10-14 days. If not in stock. lead times can be extended. We will inform you of any extended delays within 48 hours. The immunizing protein is also available for this product. Unit cost for the protein is $ 250 (2 ug). $ 305 (10 ug). and $ 445 (25 ug). |
| Gene_Id: | | 867 |
| Gene_Symbol: | | CBL |
| Omim_ID: | | 165360 NB100-869 |
| more information: | | company product webpage |