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| Catalog Code: | H00000324-A01 |
| Product Name: | APC Antibody |
| Product Description: | Mouse Polyclonal anti-APC |
| Clonality: | Polyclonal |
| ListPrice: | 225 |
| Gene ID: | 324 |
| Gene Symbol: | APC |
| Omim ID: | 135290 137215 155255 175100 276300 |
| Immunogen: | APC (NP_000029, 2744 a.a. ~ 2845 a.a) partial recombinant protein with GST tag. |
| Epitope: | NPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDS
TESSGTQSPKRHSGSYLVTSV** |
| Specificity: | APC - adenomatosis polyposis coli |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.05 ml of mouse antisera with 50% glycerol. No preservative. |
| Uses: | The quality control of this antibody is limited to Western blot on the immunizing protein. Abnovas recommended working dilutions for western analysis are as follows:1:500 dilution for ascites1:1000 for purified Ig1:500-1:1000 for polysera |
| Background: | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Host Name: | Mouse |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-Adenomatous Polyposis Coli antibody, anti-APC antibody, anti-DP2 antibody, anti-DP2.5 antibody, anti-DP3 antibody, anti-FAP antibody, anti-FPC antibody, anti-GS antibody |
| Package Size: | 0.05 ml |
| Preservative: | No preservative |
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more information: | company product webpage |