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| Catalog Code: | H00000043-M02 |
| Product Name: | ACHE Antibody |
| Product Description: | Mouse Monoclonal anti-ACHE (2C3) |
| Clone: | 2C3 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Gene ID: | 43 |
| Gene Symbol: | ACHE |
| Omim ID: | 100740, 112100 |
| Immunogen: | ACHE (NP_000656, 515 a.a. ~ 615 a.a) partial recombinant protein with GST tag. |
| Epitope: | ARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSS
YMVHWKNQFDHYSKQDRCSDL* |
| Specificity: | ACHE - acetylcholinesterase (YT blood group) |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg IgG purified Mouse ascites. |
| Uses: | Antibody reactive against cell lysate for western blot. It has also been used for ELISA. |
| Background: | Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG2a Kappa |
| Host Name: | Mouse |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu , |
| Alternate Names: | anti-ACHE antibody, anti-YT antibody, anti-acetylcholinesterase (YT blood group) antibody |
| Package Size: | 0.1 mg |
| Preservative: | No preservative |
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more information: | company product webpage |
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