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| Catalog Code: | DM3500 |
| Product Name: | Podoplanin Antibody |
| Product Description: | Mouse Monoclonal anti-Podoplanin |
| Clonality: | Monoclonal |
| ListPrice: | 455 |
| Cross Reactivity: | This antibody will detect human Podoplanin on the surface of lymphatic endothelial cells and kidney podocytes. It is not reactive with mouse podoplanin. Other species not tested. |
| Packaging: | 0.2 ml Mouse ascites. |
| Uses: | Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user. |
| Localization: | Cell Membrane |
| Background: | Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a 38 kDa membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Application Summary: | immunohistochemistry 1:50-1:200, immunoprecipitation 1:50, Western Blot >1:100, FC, 1:50 |
| Species Summary: | Hu, |
| Alternate Names: | anti-AGGRUS antibody, Anti-GLYCOPROTEIN 36 KD antibody, Anti-Glycoprotein 36 antibody, Anti-gp 36 antibody, Anti-GP 38 antibody, Anti-GP 40 antibody, Anti-gp36 antibody, Anti-GP38 antibody, Anti-GP40 antibody, Anti-HT1A 1 antibody, Anti-HT1A1 antibody, Anti-hT1alpha1 antibody, Anti-hT1alpha2 antibody, anti-Lung type I cell membrane associated glycoprotein isoform a antibody, Anti-OTS 8 antibody, Anti-OTS8 antibody, Atni-PA2.26 antibody, anti-PA2.26 antigen antibody, Anti-PDPN antibody, Anti-T1 alpha antibody, Anti-T1 ALPHA GENE antibody, Anti-T1A antibody, Anti-TIA 2 antibody, Anti-TIA2 antibody |
| Package Size: | 0.2 ml |
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