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| Catalog Code: | BC100-2503 |
| Product Name: | TERE1 Antibody |
| Product Description: | Rabbit Polyclonal anti-TERE1 |
| Clonality: | Polyclonal |
| ListPrice: | 150 |
| Concentration: | 1 mg/ml |
| Immunogen: | Reacts with residues 32-45 [PEQDRLPQRSWRQK] of the 37 kDa human TERE1 protein. |
| Cross Reactivity: | This sequence is 85% identical in mouse and rat. |
| Packaging: | 0.1 ml protein G purified Rabbit antisera. |
| Uses: | Tested by ELISA only. Recommended dilution for Western blot - Use at 1:500 to 1:1,000; IHC - Use at 1:100-1:1000. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry. |
| Background: | A novel gene designated TERE1, has a significant effect on the growth regulation in bladder cancer. The TERE1 gene maps to a chromosome locus that has been identified by loss of heterozygosity studies as a site of a putative tumor suppressor gene or genes for multiple tumor types including prostate carcinoma. Data suggest that TERE1 may be significant in prostate cancer growth regulation and the down regulation or absence of TERE1 may be an important component of the phenotype of advanced disease. Data also suggest a potential role for this gene product in the progression of bladder cancer. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | PBS containing 0.02% sodium azide. |
| Application Summary: | ELISA, |
| Package Size: | 0.1 ml |
| Preservative: | 0.02% sodium azide |
| Notes Main: | This antibody is a high-titer, purified antibody that has been tested only by ELISA. While it is expected that this antibody will perform well in Western blot and IHC applications, there is no guarantee that it will work in any application other than ELISA. |
| General References: | McGarvey T.W. et al. Oncogene. 2001 Mar 1;20(9):1042-51.; McGarvey T.W. et al. Prostate. 2003 Feb 1;54(2):144-55. |
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