| CatalogCode: | AF0910 |
| ProductName: | Prolyl 4-hydroxylase beta Antibody |
| Product Description: | Mouse Monoclonal anti-Prolyl 4-hydroxylase beta (3-2B12) - Fibroblast Marker |
| Clone: | 3-2B12 |
| Clonality: | Monoclonal |
| Immunogen: | Native human merosin M-chain |
| Epitope: | The epitope has not been determined. |
| Specificity: | This antibody specifically reacts with the beta-subunit of human P4H specifically found in fibroblasts. |
| CrossReactivity: | This antibody cross-reacts with human. The antibody has also been reported to cross react with rat P4H beta in Western blot and ELISA. Some users have reported cross reactivities with myoepithelial and urothelial cells. |
| Packaging: | 0.1 mg Affinity purified Mouse ascites. |
| Uses: | This antibody can be used in western blotting and immunohistochemistry frozen sections (FS) or paraffin section (PS). In western blot a band is seen around 60 kDa. |
| Control: | Human skin, tonsil. |
| Background: | Collagen prolyl 4-hydroxylases (P4Hs) play an essential role in the synthesis of all collagens. Two alpha and two beta subunits assemble into P4H tetramers in which protein disulfide isomerase (PDI) acts as the beta subunit. |
| ProductRef: | 1. Bai, Y. et a;. Immunological properties of monoclonal antibodies to human and rat prolyl 4-hydroxylase. J. Biochem. 99: 1563-1570, 1986. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Affinity purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | PBS, pH 7.2, containing 5 mg/ml BSA |
| ListPrice: | 375 |
| AppSummary: | WB, IHC-P, IHC-Fr |
| SpeciesSummary: | Hu, Rt |
| ALTnames: | Protein Disulfide Isomerase, Marker for Fibroblasts |
| ProteinTarget: | Human prolyl 4-hydroxylase (Fibroblast Marker) |
| PackageSize: | 0.1 mg |
| Marker: | Fibroblast Marker |
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