| item: | Mouse Anti-Bcl-1 / cyclin D1 Monoclonal Antibody, Unconjugated, Clone 5D4 |
| vendor: | Immuno-Biological Laboratories, Inc. |
| catalog number: | 11011 |
| quantity: | 200 µg, 1 ml (500 µg) |
| description: | Bcl-1/Cyclin D1 belongs to the G1 cyclins and plays a key role in cell cycle regulation during the G1/S transition by cooperating with cyclin-dependent kinases (CDKs). Its overexpression may lead to growth advantage for tumor cells by way of cell cycle progression, and actually it has been reported in various human cancers, e.g., esophageal, breast, and bladder carcinomas. Among hematolymphoid malignancies, cyclin D1 overexpression resulting from translocational activation has also been recognized in a subset of B-chronic lymphocytic leukemia (B-CLL), multiple myeloma, splenic marginal zone lymphoma, hairy cell leukemia, and mantle cell lymphoma. |
| URL: | www.ibl-america.com/ab.html |
| catid: | 3194 |
| category name: | Antibodies |
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