| PRODUCTID: | 7181 |
| CATALOG#: | ARP32651_T100 |
| PRODUCT_NAME: | APEX1 (APEX nuclease (multifunctional DNA repair enzyme) 1) Antibody |
| PRODUCTD_DESCRIPTION: | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so |
| UNIT_PRICE: | 198 |
| QTY: | 100µg |
| ACCESSION#: | NP_542379 |
| SEARCH_KEYWORD: | APEX1,APEX nuclease (multifunctional DNA repair enzyme) 1,ARP32651_T100,NP_542379,NM_080648,HGNC:587, APE, APE1, APEN, APEX, APX, HAP1, REF-1, REF1 |
| Western_Blot,link: | Suggested dilution at 1.25µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. |
| Peptide ID: | P03661 |
| Quality_Control,desc: | Rabbit IgG purified by protein A chromatography. |
| ELISA titre using peptide based assay: | 1:312500 |
| Species Reactivity: | Human |
| Immunoblot,image: | ARP32651-QC2459-WB.jpg |
| Antigen Specificity,desc: | Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human APEX1 with an internal ID of P03661 |
| Immunohistochemistry_1,image: | ARP32651-QC2459-IHC.jpg |
| Protein Size,form: | 318 |
| Key_Reference,desc: | Ding,S.Z., et al., (2004) Gastroenterology 127 (3), 845-858 |
| Reconstitution and Storage,desc: | Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 µl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Nucleotide_Accession#,form,url: | NM_080648, |
| Molecular_Weight,form: | 35 kDa |
| Gene_Symbol: | APEX1 |
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