| PRODUCTID: | | 5155 |
| CATALOG#: | | ARP32650_P050 |
| PRODUCT_NAME: | | AIRE Antibody |
| PRODUCTD_DESCRIPTION: | | The function of the protein encoded by the AIRE gene is not well defined. However it contains zinc finger motifs suggestive of a transcription factor. The protein (isoform 1) is localized to both the nucleus and cytoplasm. Defects in this gene cause the a |
| UNIT_PRICE: | | 260 |
| QTY: | | 50µg |
| ACCESSION#: | | NP_000374 |
| SEARCH_KEYWORD: | | AIRE,autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy),ARP32650_P050,NP_000374,NM_000383,O43918,HGNC:360, AIRE1, APECED, APS1, APSI, PGA1 |
| Western_Blot,link: | | Suggested dilution at 2.0µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. |
| Peptide ID: | | P03660 |
| Quality_Control,desc: | | Rabbit Ig G is purified by peptide affinity chromatography method. |
| ELISA titre using peptide based assay: | | 1:1562500 |
| Species Reactivity: | | Human,Mouse,Rat,Dog |
| Immunoblot,image: | | ARP32650-QC2086-WB.jpg |
| Antigen Specificity,desc: | | Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human AIRE with an internal ID of P03660 |
| Immunohistochemistry_1,image: | | ARP32650-QC2086-IHC.jpg |
| Protein Size,form: | | 545 |
| Key_Reference,desc: | | Akiyoshi,H., et al., (2004) J. Biol. Chem. 279 (32), 33984-33991 |
| Reconstitution and Storage,desc: | | Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 µl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Nucleotide_Accession#,form,url: | | NM_000383, |
| Swissprot_Id,form,url: | | O43918, |
| Molecular_Weight,form: | | 58kDa |
| Gene_Symbol: | | AIRE |
| more information: | | company product webpage |
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