| PRODUCTID: | 6681 |
| CATALOG#: | A112006P_50 |
| PRODUCT_NAME: | Human BACE-1 |
| PRODUCTD_DESCRIPTION: | Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by BACE |
| UNIT_PRICE: | 399 |
| QTY: | 50µg |
| ACCESSION#: | NP_036236 |
| SEARCH_KEYWORD: | BACE-1; BACE1;Alzheimerżs disease;Porteases;BACE-1 protein |
| Quality_Control,desc: | Substrate peptide based fluorescence assay. in buffer of 0.1 M sodium acetate, pH 4.5 at 37C with 5% DMSO. The increase of fluorescence (excitation at 350nm and emission at 490nm) was monitored during substrate hydrosis in a fluorescence spectrophotometer |
| Key_Reference,desc: | Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE Science 286 (5440), 735-741 (1999) |
| Gene_Symbol: | BACE-1 |
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