Gene Ontology annotation component: integral to membrane; membrane function: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity; hydrolase activity process: carbohydrate metabolism; lysosome organization and biogenesis; protein modification; protein targeting to lysosome
Gene Summary (from NCBI) Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering ...